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Proteasome Activity Is Affected by Fluctuations in Insulin-Degrading Enzyme Distribution
Insulin-Degrading-Enzyme (IDE) is a Zn(2+)-dependent peptidase highly conserved throughout evolution and ubiquitously distributed in mammalian tissues wherein it displays a prevalent cytosolic localization. We have recently demonstrated a novel Heat Shock Protein-like behaviour of IDE and its associ...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506093/ https://www.ncbi.nlm.nih.gov/pubmed/26186340 http://dx.doi.org/10.1371/journal.pone.0132455 |