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Convection-Enhanced Delivery of Carboplatin PLGA Nanoparticles for the Treatment of Glioblastoma

We currently use Convection-Enhanced Delivery (CED) of the platinum-based drug, carboplatin as a novel treatment strategy for high grade glioblastoma in adults and children. Although initial results show promise, carboplatin is not specifically toxic to tumour cells and has been associated with neur...

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Detalles Bibliográficos
Autores principales: Arshad, Azeem, Yang, Bin, Bienemann, Alison S., Barua, Neil U., Wyatt, Marcella J., Woolley, Max, Johnson, Dave E., Edler, Karen J., Gill, Steven S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506141/
https://www.ncbi.nlm.nih.gov/pubmed/26186224
http://dx.doi.org/10.1371/journal.pone.0132266