Cargando…
Leaky RAG Deficiency in Adult Patients with Impaired Antibody Production against Bacterial Polysaccharide Antigens
Loss of function mutations in the recombination activating genes RAG1 and RAG2 have been reported to cause a T(-)B(-)NK(+) type of severe combined immunodeficiency. In addition identification of hypomorphic mutations in RAG1 and RAG2 has led to an expansion of the spectrum of disease to include Omen...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506145/ https://www.ncbi.nlm.nih.gov/pubmed/26186701 http://dx.doi.org/10.1371/journal.pone.0133220 |