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Parenchymal and vascular Aβ-deposition and its effects on the degeneration of neurons and cognition in Alzheimer's disease

The deposition of the amyloid β-protein (Aβ) is one of the pathological hallmarks of Alzheimer's disease (AD). Aβ-deposits show the morphology of senile plaques and cerebral amyloid angiopathy (CAA). Senile plaques and vascular Aβ-deposits occur first in neocorti-cal areas. Then, they expand hi...

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Detalles Bibliográficos
Autores principales: Thal, Dietmar Rudolf, Griffin, W Sue T, Braak, Heiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506155/
https://www.ncbi.nlm.nih.gov/pubmed/18624777
http://dx.doi.org/10.1111/j.1582-4934.2008.00411.x