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Seladin-1/DHCR24 protects neuroblastoma cells against Aβ toxicity by increasing membrane cholesterol content

The role of brain cholesterol in Alzheimer's disease (AD) is currently a matter of debate. Experimental evidence suggests that reducing circulating and brain cholesterol protects against AD, however recent data indicate that low membrane cholesterol results in neurode-generation and that the ch...

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Detalles Bibliográficos
Autores principales: Cecchi, C, Rosati, F, Pensalfini, A, Formigli, L, Nosi, D, Liguri, G, Dichiara, F, Morello, M, Danza, G, Pieraccini, G, Peri, A, Serio, M, Stefani, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506165/
https://www.ncbi.nlm.nih.gov/pubmed/18194465
http://dx.doi.org/10.1111/j.1582-4934.2008.00216.x