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Seladin-1/DHCR24 protects neuroblastoma cells against Aβ toxicity by increasing membrane cholesterol content
The role of brain cholesterol in Alzheimer's disease (AD) is currently a matter of debate. Experimental evidence suggests that reducing circulating and brain cholesterol protects against AD, however recent data indicate that low membrane cholesterol results in neurode-generation and that the ch...
Autores principales: | Cecchi, C, Rosati, F, Pensalfini, A, Formigli, L, Nosi, D, Liguri, G, Dichiara, F, Morello, M, Danza, G, Pieraccini, G, Peri, A, Serio, M, Stefani, M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506165/ https://www.ncbi.nlm.nih.gov/pubmed/18194465 http://dx.doi.org/10.1111/j.1582-4934.2008.00216.x |
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