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Challenges and perspective of drug repurposing strategies in early phase clinical trials

Despite significant investments in the development of new agents only 5% of cancer drugs entering Phase I clinical trials are ultimately approved for routine clinical cancer care. Drug repurposing strategies using novel combinations of previously tested anticancer agents could reduce the cost and im...

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Detalles Bibliográficos
Autores principales: Kato, Shumei, Moulder, Stacy L., Ueno, Naoto T., Wheler, Jennifer J., Meric-Bernstam, Funda, Kurzrock, Razelle, Janku, Filip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506360/
https://www.ncbi.nlm.nih.gov/pubmed/26244164