Oncogenic CXCL10 signalling drives metastasis development and poor clinical outcome

BACKGROUND: The CXCL10/CXCR3 signalling mediates paracrine interactions between tumour and stromal cells that govern leukocyte trafficking and angiogenesis. Emerging data implicate noncanonical CXCL10/CXCR3 signalling in tumourigenesis and metastasis. However, little is known regarding the role for...

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Detalles Bibliográficos
Autores principales: Wightman, S C, Uppal, A, Pitroda, S P, Ganai, S, Burnette, B, Stack, M, Oshima, G, Khan, S, Huang, X, Posner, M C, Weichselbaum, R R, Khodarev, N N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506383/
https://www.ncbi.nlm.nih.gov/pubmed/26042934
http://dx.doi.org/10.1038/bjc.2015.193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506383/
https://www.ncbi.nlm.nih.gov/pubmed/26042934
http://dx.doi.org/10.1038/bjc.2015.193

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