Tumour-suppressive microRNA-144-5p directly targets CCNE1/2 as potential prognostic markers in bladder cancer

BACKGROUND: Analysis of a microRNA (miRNA) expression signature of bladder cancer (BC) by deep-sequencing revealed that clustered miRNAs microRNA (miR)-451a, miR-144-3p, and miR-144-5p were significantly downregulated in BC tissues. We hypothesised that these miRNAs function as tumour suppressors in...

Descripción completa

Detalles Bibliográficos
Autores principales: Matsushita, R, Seki, N, Chiyomaru, T, Inoguchi, S, Ishihara, T, Goto, Y, Nishikawa, R, Mataki, H, Tatarano, S, Itesako, T, Nakagawa, M, Enokida, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506384/
https://www.ncbi.nlm.nih.gov/pubmed/26057453
http://dx.doi.org/10.1038/bjc.2015.195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506384/
https://www.ncbi.nlm.nih.gov/pubmed/26057453
http://dx.doi.org/10.1038/bjc.2015.195

Ejemplares similares