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The expression of tumour suppressors and proto-oncogenes in tissues susceptible to their hereditary cancers
BACKGROUND: Studies of familial cancers have found that only a small subset of tissues are affected by inherited mutations in a given tumour suppressor gene (TSG) or proto-oncogene (POG), even though the mutation is present in all tissues. Previous tests have shown that tissue specificity is not due...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506389/ https://www.ncbi.nlm.nih.gov/pubmed/26079304 http://dx.doi.org/10.1038/bjc.2015.205 |