Dual inhibition of survivin and MAOA synergistically impairs growth of PTEN-negative prostate cancer

BACKGROUND: Survivin and monoamine oxidase A (MAOA) levels are elevated in prostate cancer (PCa) compared to normal prostate glands. However, the relationship between survivin and MAOA in PCa is unclear. METHODS: We examined MAOA expression in the prostate lobes of a conditional PTEN-deficient mouse...

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Detalles Bibliográficos
Autores principales: Xu, S, Adisetiyo, H, Tamura, S, Grande, F, Garofalo, A, Roy-Burman, P, Neamati, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506394/
https://www.ncbi.nlm.nih.gov/pubmed/26103574
http://dx.doi.org/10.1038/bjc.2015.228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506394/
https://www.ncbi.nlm.nih.gov/pubmed/26103574
http://dx.doi.org/10.1038/bjc.2015.228

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