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TKTL1 expression in human malign and benign cell lines

BACKGROUND: Overexpression of transketolase-like 1 protein TKTL1 in cancer cells has been reported to correlate with enhanced glycolysis and lactic acid production. Furthermore, enhanced TKTL1 expression was put into context with resistance to chemotherapy and ionizing radiation. Here, a panel of hu...

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Detalles Bibliográficos
Autores principales: Kämmerer, Ulrike, Gires, Olivier, Pfetzer, Nadja, Wiegering, Armin, Klement, Rainer Johannes, Otto, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506423/
https://www.ncbi.nlm.nih.gov/pubmed/26187043
http://dx.doi.org/10.1186/1471-2407-15-2