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Evidence for a distinct neuro-immune signature in rats that develop behavioural disability after nerve injury

BACKGROUND: Chronic neuropathic pain is a neuro-immune disorder, characterised by allodynia, hyperalgesia and spontaneous pain, as well as debilitating affective-motivational disturbances (e.g., reduced social interactions, sleep-wake cycle disruption, anhedonia, and depression). The role of the imm...

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Detalles Bibliográficos
Autores principales: Austin, Paul J, Berglund, Annika M, Siu, Sherman, Fiore, Nathan T, Gerke-Duncan, Michelle B, Ollerenshaw, Suzanne L, Leigh, Sarah-Jane, Kunjan, Priya A, Kang, James WM, Keay, Kevin A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506439/
https://www.ncbi.nlm.nih.gov/pubmed/25986444
http://dx.doi.org/10.1186/s12974-015-0318-4