Optimal selection of natural killer cells to kill myeloma: the role of HLA-E and NKG2A

Immunotherapy with allogeneic natural killer (NK) cells offers therapeutic perspectives for multiple myeloma patients. Here, we aimed to refine NK cell therapy by evaluation of the relevance of HLA-class I and HLA-E for NK anti-myeloma reactivity. We show that HLA-class I was strongly expressed on t...

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Detalles Bibliográficos
Autores principales: Sarkar, Subhashis, van Gelder, Michel, Noort, Willy, Xu, Yunping, Rouschop, Kasper M. A., Groen, Richard, Schouten, Harry C., Tilanus, Marcel G. J., Germeraad, Wilfred T. V., Martens, Anton C. M., Bos, Gerard M. J., Wieten, Lotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506464/
https://www.ncbi.nlm.nih.gov/pubmed/25920521
http://dx.doi.org/10.1007/s00262-015-1694-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506464/
https://www.ncbi.nlm.nih.gov/pubmed/25920521
http://dx.doi.org/10.1007/s00262-015-1694-4

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