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Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development

BACKGROUND: The pervasive expression of circular RNA is a recently discovered feature of gene expression in highly diverged eukaryotes, but the functions of most circular RNAs are still unknown. Computational methods to discover and quantify circular RNA are essential. Moreover, discovering biologic...

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Detalles Bibliográficos
Autores principales: Szabo, Linda, Morey, Robert, Palpant, Nathan J., Wang, Peter L., Afari, Nastaran, Jiang, Chuan, Parast, Mana M., Murry, Charles E., Laurent, Louise C., Salzman, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506483/
https://www.ncbi.nlm.nih.gov/pubmed/26076956
http://dx.doi.org/10.1186/s13059-015-0690-5