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Structural basis for catalytically restrictive dynamics of a high-energy enzyme state

An emerging paradigm in enzymology is that transient high-energy structural states play crucial roles in enzymatic reaction cycles. Generally, these high-energy or ‘invisible' states cannot be studied directly at atomic resolution using existing structural and spectroscopic techniques owing to...

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Detalles Bibliográficos
Autores principales: Kovermann, Michael, Ådén, Jörgen, Grundström, Christin, Elisabeth Sauer-Eriksson, A., Sauer, Uwe H., Wolf-Watz, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506515/
https://www.ncbi.nlm.nih.gov/pubmed/26138143
http://dx.doi.org/10.1038/ncomms8644