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Cryo-EM reveals the conformation of a substrate analogue in the human 20S proteasome core
The proteasome is a highly regulated protease complex fundamental for cell homeostasis and controlled cell cycle progression. It functions by removing a wide range of specifically tagged proteins, including key cellular regulators. Here we present the structure of the human 20S proteasome core bound...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Pub. Group
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506541/ https://www.ncbi.nlm.nih.gov/pubmed/26133119 http://dx.doi.org/10.1038/ncomms8573 |