Structure and Mechanism of an Aspartimide-Dependent Peptide Ligase in Human Legumain**

Peptide ligases expand the repertoire of genetically encoded protein architectures by synthesizing new peptide bonds, energetically driven by ATP or NTPs. Here, we report the discovery of a genuine ligase activity in human legumain (AEP) which has important roles in immunity and tumor progression th...

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Detalles Bibliográficos
Autores principales: Dall, Elfriede, Fegg, Julia C, Briza, Peter, Brandstetter, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2015
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506564/
https://www.ncbi.nlm.nih.gov/pubmed/25630877
http://dx.doi.org/10.1002/anie.201409135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506564/
https://www.ncbi.nlm.nih.gov/pubmed/25630877
http://dx.doi.org/10.1002/anie.201409135

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