Identification of sequences common to more than one therapeutic target to treat complex diseases: simulating the high variance in sequence interactivity evolved to modulate robust phenotypes

BACKGROUND: Genome-wide association studies show that most human traits and diseases are caused by a combination of environmental and genetic causes, with each one of these having a relatively small effect. In contrast, most therapies based on macromolecules like antibodies, antisense oligonucleotid...

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Detalles Bibliográficos
Autor principal: Varela, Miguel Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506634/
https://www.ncbi.nlm.nih.gov/pubmed/26187740
http://dx.doi.org/10.1186/s12864-015-1727-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506634/
https://www.ncbi.nlm.nih.gov/pubmed/26187740
http://dx.doi.org/10.1186/s12864-015-1727-6

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