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Hypoxia Induces a Metabolic Shift and Enhances the Stemness and Expansion of Cochlear Spiral Ganglion Stem/Progenitor Cells

Previously, we demonstrated that hypoxia (1% O(2)) enhances stemness markers and expands the cell numbers of cochlear stem/progenitor cells (SPCs). In this study, we further investigated the long-term effect of hypoxia on stemness and the bioenergetic status of cochlear spiral ganglion SPCs cultured...

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Detalles Bibliográficos
Autores principales: Chen, Hsin-Chien, Lee, Jen-Tin, Shih, Cheng-Ping, Chao, Ting-Ting, Sytwu, Huey-Kang, Li, Shiue-Li, Fang, Mei-Cho, Chen, Hang-Kang, Lin, Yi-Chun, Kuo, Chao-Yin, Wang, Chih-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506838/
https://www.ncbi.nlm.nih.gov/pubmed/26236724
http://dx.doi.org/10.1155/2015/359537