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Hypoxia Induces a Metabolic Shift and Enhances the Stemness and Expansion of Cochlear Spiral Ganglion Stem/Progenitor Cells
Previously, we demonstrated that hypoxia (1% O(2)) enhances stemness markers and expands the cell numbers of cochlear stem/progenitor cells (SPCs). In this study, we further investigated the long-term effect of hypoxia on stemness and the bioenergetic status of cochlear spiral ganglion SPCs cultured...
Autores principales: | Chen, Hsin-Chien, Lee, Jen-Tin, Shih, Cheng-Ping, Chao, Ting-Ting, Sytwu, Huey-Kang, Li, Shiue-Li, Fang, Mei-Cho, Chen, Hang-Kang, Lin, Yi-Chun, Kuo, Chao-Yin, Wang, Chih-Hung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506838/ https://www.ncbi.nlm.nih.gov/pubmed/26236724 http://dx.doi.org/10.1155/2015/359537 |
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