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Integrative Genomics Identifies YY1AP1 as an Oncogenic Driver in EpCAM(+) AFP(+) Hepatocellular Carcinoma

Identification of key drivers and new therapeutic targets is important given the poor prognosis for hepatocellular carcinoma (HCC) patients, particularly those ineligible for surgical resection or liver transplant. However, the approach to identify such driver genes is facing significant challenges...

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Detalles Bibliográficos
Autores principales: Zhao, Xuelian, Parpart, Sonya, Takai, Atsushi, Roessler, Stephanie, Budhu, Anuradha, Yu, Zhipeng, Blank, Michael, Zhang, Ying E., Jia, Hu-Liang, Ye, Qing-Hai, Qin, Lun-Xiu, Tang, Zhao-You, Thorgeirsson, Snorri S., Wang, Xin Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506915/
https://www.ncbi.nlm.nih.gov/pubmed/25597408
http://dx.doi.org/10.1038/onc.2014.438