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Integrative Genomics Identifies YY1AP1 as an Oncogenic Driver in EpCAM(+) AFP(+) Hepatocellular Carcinoma
Identification of key drivers and new therapeutic targets is important given the poor prognosis for hepatocellular carcinoma (HCC) patients, particularly those ineligible for surgical resection or liver transplant. However, the approach to identify such driver genes is facing significant challenges...
Autores principales: | Zhao, Xuelian, Parpart, Sonya, Takai, Atsushi, Roessler, Stephanie, Budhu, Anuradha, Yu, Zhipeng, Blank, Michael, Zhang, Ying E., Jia, Hu-Liang, Ye, Qing-Hai, Qin, Lun-Xiu, Tang, Zhao-You, Thorgeirsson, Snorri S., Wang, Xin Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506915/ https://www.ncbi.nlm.nih.gov/pubmed/25597408 http://dx.doi.org/10.1038/onc.2014.438 |
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