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Histone H3 Ser57 and Thr58 phosphorylation in the brain of 5XFAD mice

Alzheimer’s disease has been shown to have a global reduction in gene expression, called an epigenetic blockade, which may be regulated by histone post-translational modifications. Histone H3 has been shown to be highly regulated by phosphorylation. We, therefore, chose H3 for investigation of phosp...

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Detalles Bibliográficos
Autores principales: Anderson, Kyle W., Mast, Natalia, Pikuleva, Irina A., Turko, Illarion V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506931/
https://www.ncbi.nlm.nih.gov/pubmed/26199864
http://dx.doi.org/10.1016/j.fob.2015.06.009