The schizophrenia risk gene product miR-137 alters presynaptic plasticity

Non-coding variants in the human MIR137 gene locus increase schizophrenia risk at a genome-wide significance level. However, the functional consequence of these risk alleles is unknown. Here, we examined induced human neurons harboring the minor alleles of four disease-associated single nucleotide p...

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Detalles Bibliográficos
Autores principales: Siegert, Sandra, Seo, Jinsoo, Kwon, Ester J., Rudenko, Andrii, Cho, Sukhee, Wang, Wenyuan, Flood, Zachary, Martorell, Anthony J., Ericsson, Maria, Mungenast, Alison E., Tsai, Li-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506960/
https://www.ncbi.nlm.nih.gov/pubmed/26005852
http://dx.doi.org/10.1038/nn.4023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506960/
https://www.ncbi.nlm.nih.gov/pubmed/26005852
http://dx.doi.org/10.1038/nn.4023

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