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The schizophrenia risk gene product miR-137 alters presynaptic plasticity
Non-coding variants in the human MIR137 gene locus increase schizophrenia risk at a genome-wide significance level. However, the functional consequence of these risk alleles is unknown. Here, we examined induced human neurons harboring the minor alleles of four disease-associated single nucleotide p...
Autores principales: | Siegert, Sandra, Seo, Jinsoo, Kwon, Ester J., Rudenko, Andrii, Cho, Sukhee, Wang, Wenyuan, Flood, Zachary, Martorell, Anthony J., Ericsson, Maria, Mungenast, Alison E., Tsai, Li-Huei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506960/ https://www.ncbi.nlm.nih.gov/pubmed/26005852 http://dx.doi.org/10.1038/nn.4023 |
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