Probing the target search of DNA-binding proteins in mammalian cells using TetR as model searcher

Many cellular functions rely on DNA-binding proteins finding and associating to specific sites in the genome. Yet the mechanisms underlying the target search remain poorly understood, especially in the case of the highly organized mammalian cell nucleus. Using as a model Tet repressors (TetRs) searc...

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Detalles Bibliográficos
Autores principales: Normanno, Davide, Boudarène, Lydia, Dugast-Darzacq, Claire, Chen, Jiji, Richter, Christian, Proux, Florence, Bénichou, Olivier, Voituriez, Raphaël, Darzacq, Xavier, Dahan, Maxime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507003/
https://www.ncbi.nlm.nih.gov/pubmed/26151127
http://dx.doi.org/10.1038/ncomms8357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507003/
https://www.ncbi.nlm.nih.gov/pubmed/26151127
http://dx.doi.org/10.1038/ncomms8357

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