Concentration- and chromosome-organization-dependent regulator unbinding from DNA for transcription regulation in living cells

Binding and unbinding of transcription regulators at operator sites constitute a primary mechanism for gene regulation. While many cellular factors are known to regulate their binding, little is known on how cells can modulate their unbinding for regulation. Using nanometer-precision single-molecule...

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Detalles Bibliográficos
Autores principales: Chen, Tai-Yen, Santiago, Ace George, Jung, Won, Krzemiński, Łukasz, Yang, Feng, Martell, Danya J., Helmann, John D., Chen, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507017/
https://www.ncbi.nlm.nih.gov/pubmed/26145755
http://dx.doi.org/10.1038/ncomms8445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507017/
https://www.ncbi.nlm.nih.gov/pubmed/26145755
http://dx.doi.org/10.1038/ncomms8445

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