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Concentration- and chromosome-organization-dependent regulator unbinding from DNA for transcription regulation in living cells
Binding and unbinding of transcription regulators at operator sites constitute a primary mechanism for gene regulation. While many cellular factors are known to regulate their binding, little is known on how cells can modulate their unbinding for regulation. Using nanometer-precision single-molecule...
Autores principales: | Chen, Tai-Yen, Santiago, Ace George, Jung, Won, Krzemiński, Łukasz, Yang, Feng, Martell, Danya J., Helmann, John D., Chen, Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507017/ https://www.ncbi.nlm.nih.gov/pubmed/26145755 http://dx.doi.org/10.1038/ncomms8445 |
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