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Thymic Crosstalk Coordinates Medulla Organization and T-Cell Tolerance Induction

The thymus ensures the generation of a functional and highly diverse T-cell repertoire. The thymic medulla, which is mainly composed of medullary thymic epithelial cells (mTECs) and dendritic cells (DCs), provides a specialized microenvironment dedicated to the establishment of T-cell tolerance. mTE...

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Detalles Bibliográficos
Autores principales: Lopes, Noëlla, Sergé, Arnauld, Ferrier, Pierre, Irla, Magali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507079/
https://www.ncbi.nlm.nih.gov/pubmed/26257733
http://dx.doi.org/10.3389/fimmu.2015.00365