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Thymic Crosstalk Coordinates Medulla Organization and T-Cell Tolerance Induction
The thymus ensures the generation of a functional and highly diverse T-cell repertoire. The thymic medulla, which is mainly composed of medullary thymic epithelial cells (mTECs) and dendritic cells (DCs), provides a specialized microenvironment dedicated to the establishment of T-cell tolerance. mTE...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507079/ https://www.ncbi.nlm.nih.gov/pubmed/26257733 http://dx.doi.org/10.3389/fimmu.2015.00365 |