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Aspirin-induced histone acetylation in endothelial cells enhances synthesis of the secreted isoform of netrin-1 thus inhibiting monocyte vascular infiltration

BACKGROUND AND PURPOSE: There are conflicting data regarding whether netrin-1 retards or accelerates atherosclerosis progression, as it can lead either to monocyte repulsion from or retention within plaques depending on its cellular source. We investigated the effect of aspirin, which is widely used...

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Detalles Bibliográficos
Autores principales: Passacquale, Gabriella, Phinikaridou, Alkystis, Warboys, Christina, Cooper, Margaret, Lavin, Begona, Alfieri, Alessio, Andia, Marcelo E, Botnar, Rene M, Ferro, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507159/
https://www.ncbi.nlm.nih.gov/pubmed/25824964
http://dx.doi.org/10.1111/bph.13144