LRP-1-mediated intracellular antibody delivery to the Central Nervous System

The blood-brain barrier (BBB) is by far the most important target in developing new approaches to improve delivery of drugs and diagnostic tools into the Central Nervous System (CNS). Here we report the engineering of pH- sensitive polymersomes (synthetic vesicles formed by amphiphilic copolymers) t...

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Detalles Bibliográficos
Autores principales: Tian, Xiaohe, Nyberg, Sophie, S. Sharp, Paul, Madsen, Jeppe, Daneshpour, Nooshin, Armes, Steven P., Berwick, Jason, Azzouz, Mimoun, Shaw, Pamela, Abbott, N. Joan, Battaglia, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507173/
https://www.ncbi.nlm.nih.gov/pubmed/26189707
http://dx.doi.org/10.1038/srep11990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507173/
https://www.ncbi.nlm.nih.gov/pubmed/26189707
http://dx.doi.org/10.1038/srep11990

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