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Sulfonoquinovosyl diacylglyceride selectively targets acute lymphoblastic leukemia cells and exerts potent anti-leukemic effects in vivo

DNA topoisomerase II inhibitors e.g. doxorubicin and etoposide are currently used in the chemotherapy for acute lymphoblastic leukemia (ALL). These inhibitors have serious side effects during the chemotherapy e.g. cardiotoxicity and secondary malignancies. In this study we show that sulfonoquinovosy...

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Detalles Bibliográficos
Autores principales: Jain, Chetan Kumar, Pradhan, Bhola Shankar, Banerjee, Sukdeb, Mondal, Nirup Bikash, Majumder, Subeer S., Bhattacharyya, Madhumita, Chakrabarti, Saikat, Roychoudhury, Susanta, Majumder, Hemanta Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507174/
https://www.ncbi.nlm.nih.gov/pubmed/26189912
http://dx.doi.org/10.1038/srep12082