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Bioresponsive antisense DNA gold nanobeacons as a hybrid in vivo theranostics platform for the inhibition of cancer cells and metastasis

Gold nanobeacons can be used as a powerful tool for cancer theranostics. Here, we proposed a nanomaterial platform based on gold nanobeacons to detect, target and inhibit the expression of a mutant Kras gene in an in vivo murine gastric cancer model. The conjugation of fluorescently-labeled antisens...

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Detalles Bibliográficos
Autores principales: Bao, Chenchen, Conde, João, Curtin, James, Artzi, Natalie, Tian, Furong, Cui, Daxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507177/
https://www.ncbi.nlm.nih.gov/pubmed/26189409
http://dx.doi.org/10.1038/srep12297