PDGFRβ signaling regulates local inflammation and synergizes with hypercholesterolemia to promote atherosclerosis

Platelet-derived growth factor (PDGF) is a mitogen and chemoattractant for vascular smooth muscle cells (VSMCs). However, the direct effects of PDGF receptor β (PDGFRβ) activation on VSMCs have not been studied in the context of atherosclerosis. Here, we present a new mouse model of atherosclerosis...

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Detalles Bibliográficos
Autores principales: He, Chaoyong, Medley, Shayna C., Hu, Taishan, Hinsdale, Myron E., Lupu, Florea, Virmani, Renu, Olson, Lorin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507293/
https://www.ncbi.nlm.nih.gov/pubmed/26183159
http://dx.doi.org/10.1038/ncomms8770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507293/
https://www.ncbi.nlm.nih.gov/pubmed/26183159
http://dx.doi.org/10.1038/ncomms8770

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