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IL-15–PI3K–AKT–mTOR: A Critical Pathway in the Life Journey of Natural Killer Cells

Among numerous cytokines modulating natural killer (NK) cell function, interleukin 15 (IL-15) exerts a broad range of effect from development and homeostasis, to activation of mature NK cells during infection. Its significance is further highlighted by clinical trials in which IL-15 is being used to...

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Detalles Bibliográficos
Autores principales: Ali, Alaa Kassim, Nandagopal, Neethi, Lee, Seung-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507451/
https://www.ncbi.nlm.nih.gov/pubmed/26257729
http://dx.doi.org/10.3389/fimmu.2015.00355