Cargando…
IL-15–PI3K–AKT–mTOR: A Critical Pathway in the Life Journey of Natural Killer Cells
Among numerous cytokines modulating natural killer (NK) cell function, interleukin 15 (IL-15) exerts a broad range of effect from development and homeostasis, to activation of mature NK cells during infection. Its significance is further highlighted by clinical trials in which IL-15 is being used to...
Autores principales: | Ali, Alaa Kassim, Nandagopal, Neethi, Lee, Seung-Hwan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507451/ https://www.ncbi.nlm.nih.gov/pubmed/26257729 http://dx.doi.org/10.3389/fimmu.2015.00355 |
Ejemplares similares
-
The Critical Role of IL-15–PI3K–mTOR Pathway in Natural Killer Cell Effector Functions
por: Nandagopal, Neethi, et al.
Publicado: (2014) -
PI3K/AKT/mTOR Pathway in Angiogenesis
por: Karar, Jayashree, et al.
Publicado: (2011) -
Targeting PI3K/Akt/mTOR Signaling in Cancer
por: Porta, Camillo, et al.
Publicado: (2014) -
PI3K/Akt/mTOR inhibitors in breast cancer
por: Lee, Joycelyn JX, et al.
Publicado: (2015) -
Targeting the PI3K/Akt/mTOR Pathway – Beyond Rapalogs
por: Markman, Ben, et al.
Publicado: (2010)