Overexpression of Bovine FcRn in Mice Enhances T-Dependent Immune Responses by Amplifying T Helper Cell Frequency and Germinal Center Enlargement in the Spleen

The neonatal Fc receptor (FcRn) plays key roles in IgG and albumin homeostasis, maternal IgG transport, and antigen presentation of IgG-opsonized antigens. Previously, we reported that transgenic (Tg) mice that overexpress the bovine FcRn (bFcRn) have augmented T-dependent humoral immune response wi...

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Detalles Bibliográficos
Autores principales: Schneider, Zita, Jani, Péter Károly, Szikora, Bence, Végh, Attila, Kövesdi, Dorottya, Iliás, Attila, Cervenak, Judit, Balogh, Péter, Kurucz, István, Kacskovics, Imre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507463/
https://www.ncbi.nlm.nih.gov/pubmed/26257730
http://dx.doi.org/10.3389/fimmu.2015.00357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507463/
https://www.ncbi.nlm.nih.gov/pubmed/26257730
http://dx.doi.org/10.3389/fimmu.2015.00357

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