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Regulatory B cells preferentially accumulate in tumor-draining lymph nodes and promote tumor growth

Our previous studies found that B16-F10 melanoma growth in the rear footpad of immunocompetent mice induces marked B cell accumulation within tumor-draining popliteal lymph nodes (TDLN). This B cell accumulation drives TDLN remodeling that precedes and promotes metastasis, indicating a tumor-promoti...

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Detalles Bibliográficos
Autores principales: Ganti, Sheila N., Albershardt, Tina C., Iritani, Brian M., Ruddell, Alanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507466/
https://www.ncbi.nlm.nih.gov/pubmed/26193241
http://dx.doi.org/10.1038/srep12255