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Self-organized Kidney Rudiments: Prospects for Better in vitro Nephrotoxicity Assays
Kidneys are essential to life but vulnerable to a range of toxicants, including therapeutic drugs and their metabolites. Indeed, nephrotoxicity is often a limiting factor in both drug use and drug development. Most toxicants damage kidneys by one of four mechanisms: damage to the membrane and its ju...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Libertas Academica
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507472/ https://www.ncbi.nlm.nih.gov/pubmed/26244008 http://dx.doi.org/10.4137/BMI.S20056 |