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Dynamic Equilibria of Short-Range Electrostatic Interactions at Molecular Interfaces of Protein–DNA Complexes

[Image: see text] Intermolecular ion pairs (salt bridges) are crucial for protein–DNA association. For two protein–DNA complexes, we demonstrate that the ion pairs of protein side-chain NH(3)(+) and DNA phosphate groups undergo dynamic transitions between distinct states in which the charged moietie...

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Detalles Bibliográficos
Autores principales: Chen, Chuanying, Esadze, Alexandre, Zandarashvili, Levani, Nguyen, Dan, Pettitt, B. Montgomery, Iwahara, Junji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507475/
https://www.ncbi.nlm.nih.gov/pubmed/26207171
http://dx.doi.org/10.1021/acs.jpclett.5b01134