Luciferin Amides Enable in Vivo Bioluminescence Detection of Endogenous Fatty Acid Amide Hydrolase Activity

[Image: see text] Firefly luciferase is homologous to fatty acyl-CoA synthetases. We hypothesized that the firefly luciferase substrate d-luciferin and its analogs are fatty acid mimics that are ideally suited to probe the chemistry of enzymes that release fatty acid products. Here, we synthesized l...

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Detalles Bibliográficos
Autores principales: Mofford, David M., Adams, Spencer T., Reddy, G. S. Kiran Kumar, Reddy, Gadarla Randheer, Miller, Stephen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507478/
https://www.ncbi.nlm.nih.gov/pubmed/26120870
http://dx.doi.org/10.1021/jacs.5b04357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507478/
https://www.ncbi.nlm.nih.gov/pubmed/26120870
http://dx.doi.org/10.1021/jacs.5b04357

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