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Luciferin Amides Enable in Vivo Bioluminescence Detection of Endogenous Fatty Acid Amide Hydrolase Activity

[Image: see text] Firefly luciferase is homologous to fatty acyl-CoA synthetases. We hypothesized that the firefly luciferase substrate d-luciferin and its analogs are fatty acid mimics that are ideally suited to probe the chemistry of enzymes that release fatty acid products. Here, we synthesized l...

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Detalles Bibliográficos
Autores principales:	Mofford, David M., Adams, Spencer T., Reddy, G. S. Kiran Kumar, Reddy, Gadarla Randheer, Miller, Stephen C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2015
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507478/ https://www.ncbi.nlm.nih.gov/pubmed/26120870 http://dx.doi.org/10.1021/jacs.5b04357

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