Batf3 maintains Irf8 autoactivation for commitment of a CD8α(+) cDC clonogenic progenitor

The transcription factors Batf3 and IRF8 are required for development of CD8α(+) conventional dendritic cells (cDCs), but the basis for their actions was unclear. Here, we identify two novel Zbtb46(+) progenitors that separately generate CD8α(+) and CD4(+) cDCs and arise directly from the common DC...

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Detalles Bibliográficos
Autores principales: Grajales-Reyes, Gary E., Iwata, Arifumi, Albring, Jörn, Wu, Xiaodi, Tussiwand, Roxane, Wumesh, KC, Kretzer, Nicole M., Briseño, Carlos G., Durai, Vivek, Bagadia, Prachi, Haldar, Malay, Schönheit, Jörg, Rosenbauer, Frank, Murphy, Theresa L., Murphy, Kenneth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507574/
https://www.ncbi.nlm.nih.gov/pubmed/26054719
http://dx.doi.org/10.1038/ni.3197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507574/
https://www.ncbi.nlm.nih.gov/pubmed/26054719
http://dx.doi.org/10.1038/ni.3197

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