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Inhibition of Granulomatous Inflammation and Prophylactic Treatment of Schistosomiasis with a Combination of Edelfosine and Praziquantel

BACKGROUND: Schistosomiasis is the third most devastating tropical disease worldwide caused by blood flukes of the genus Schistosoma. This parasitic disease is due to immunologic reactions to Schistosoma eggs trapped in tissues. Egg-released antigens stimulate tissue-destructive inflammatory and gra...

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Detalles Bibliográficos
Autores principales: Yepes, Edward, Varela-M, Rubén E., López-Abán, Julio, Rojas-Caraballo, Jose, Muro, Antonio, Mollinedo, Faustino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507859/
https://www.ncbi.nlm.nih.gov/pubmed/26191954
http://dx.doi.org/10.1371/journal.pntd.0003893