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Roflumilast Prevents the Metabolic Effects of Bleomycin-Induced Fibrosis in a Murine Model

Fibrotic remodeling is a process common to chronic lung diseases such as chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, acute respiratory distress syndrome and asthma. Based on preclinical studies phosphodiesterase 4 (PDE4) inhibitors may exhibit beneficial anti-inflammatory and a...

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Detalles Bibliográficos
Autores principales: Milara, Javier, Morcillo, Esteban, Monleon, Daniel, Tenor, Herman, Cortijo, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507994/
https://www.ncbi.nlm.nih.gov/pubmed/26192616
http://dx.doi.org/10.1371/journal.pone.0133453