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Roflumilast Prevents the Metabolic Effects of Bleomycin-Induced Fibrosis in a Murine Model
Fibrotic remodeling is a process common to chronic lung diseases such as chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, acute respiratory distress syndrome and asthma. Based on preclinical studies phosphodiesterase 4 (PDE4) inhibitors may exhibit beneficial anti-inflammatory and a...
Autores principales: | Milara, Javier, Morcillo, Esteban, Monleon, Daniel, Tenor, Herman, Cortijo, Julio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507994/ https://www.ncbi.nlm.nih.gov/pubmed/26192616 http://dx.doi.org/10.1371/journal.pone.0133453 |
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