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Regulation of Renal Hemodynamics and Function by RGS2

Regulator of G protein signaling 2 (RGS2) controls G protein coupled receptor (GPCR) signaling by acting as a GTPase-activating protein for heterotrimeric G proteins. Certain Rgs2 gene mutations have been linked to human hypertension. Renal RGS2 deficiency is sufficient to cause hypertension in mice...

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Detalles Bibliográficos
Autores principales: Osei-Owusu, Patrick, Owens, Elizabeth A., Jie, Li, Reis, Janaina S., Forrester, Steven J., Kawai, Tatsuo, Eguchi, Satoru, Singh, Harpreet, Blumer, Kendall J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508038/
https://www.ncbi.nlm.nih.gov/pubmed/26193676
http://dx.doi.org/10.1371/journal.pone.0132594