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Regulation of Renal Hemodynamics and Function by RGS2
Regulator of G protein signaling 2 (RGS2) controls G protein coupled receptor (GPCR) signaling by acting as a GTPase-activating protein for heterotrimeric G proteins. Certain Rgs2 gene mutations have been linked to human hypertension. Renal RGS2 deficiency is sufficient to cause hypertension in mice...
Autores principales: | Osei-Owusu, Patrick, Owens, Elizabeth A., Jie, Li, Reis, Janaina S., Forrester, Steven J., Kawai, Tatsuo, Eguchi, Satoru, Singh, Harpreet, Blumer, Kendall J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508038/ https://www.ncbi.nlm.nih.gov/pubmed/26193676 http://dx.doi.org/10.1371/journal.pone.0132594 |
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