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Pancreatic Neuroendocrine Tumors in Mice Deficient in Proglucagon-Derived Peptides
Animal models with defective glucagon action show hyperplasia of islet α-cells, however, the regulatory mechanisms underlying the proliferation of islet endocrine cells remain largely to be elucidated. The Gcg(gfp/gfp) mice, which are homozygous for glucagon/green fluorescent protein knock-in allele...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508046/ https://www.ncbi.nlm.nih.gov/pubmed/26192435 http://dx.doi.org/10.1371/journal.pone.0133812 |